From a Keyword or the PDB entry of a complex, you can browse:

• structural homologs for every chain in other complexes
• structural interologs for every interface
• retrieve pre-computed sequence alignments in diverse species

From 1 or 2 sequences of interacting partners:

• build 2 multiple sequence alignments with the same species ordered in each
• query the InterEvol database with alignments using profile-profile comparison method

Visualize structure vs sequence alignment at the complex interface

• A dedicated Pymol plugin is provided
• Alignment views in Pymol are interactively restricted to the residues selected at the interface

Scoring models of docked complexes using evolution

• Evaluate models likelihood using multi-body statistical potential coupled to evolution
• Cluster ensembles of solutions