Morpheus
Prediction of Transcription Factors Binding Sites based on Position Weight Matrix
Score calculation
This tool calculates the scores of TFBS present in a list of DNA sequences :
- Option “All” determines the score of all sites in each DNA sequence and generate quantitative profiles. In this case, you can work with a maximum of 100 DNA sequences and a maximum of 1 000 000 nucleotides.
- Option “Limit” gives similar results than “All” but only site with a score higher than a given limit will be shown. In this case, you can work with a maximum of 100 DNA sequences and a maximum of 1 000 000 nucleotides.
- Option “Best” gives the site with the best score in each DNA sequence. Result of this option can be used as input for the ROC-AUC tool. In this case, you can work with a maximum of 5000 DNA sequences and a maximum of 10 000 000 nucleotides.
This tool also gives a graphic output showing the position of the better sites in each sequence (options “All” and “Limit”) and a histogram of showing the scores distribution.
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