Morpheus
Prediction of Transcription Factors Binding Sites based on Position Weight Matrix
Occupancy
This tool calculates Transcription Factor Occupancy as the relative expected number of bound transcription factor molecules (Roider et al., 2007) of each DNA sequence.
- Option “All” use all sites in each sequence for Occupancy calculation. In this case, you can work with a maximum of 5000 DNA sequences and a maximum of 10 000 000 nucleotides.
- Option “Limit” gives similar results than “All“ but a score limit can be specified so all sites with score worse than the limit will not be used. In this case, you can work with a maximum of 5000 DNA sequences and a maximum of 10 000 000 nucleotides.
This tool also gives a graphic output showing occupancy of each sequence and a histogram of occupancy distribution. The Result file can be used as input for ROC-AUC tool.
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